Using your Pirelli Cinturato Gravel 700 x 45C tyres is easy. Just fit them onto your 700 x 45C wheels and you're good to go. These tyres are great for various terrains, but remember to adjust your speed according to the surface. When riding on gravel or dirt roads, be a bit more cautious as the grip might vary. As for maintenance, check the tyre pressure regularly to keep them rolling smoothly. After a muddy ride, give them a good wash to remove any dirt. If you notice any cuts or significant wear, it might be time to replace them. With proper use and care, these tyres will serve you well on all your cycling trips.